We wash our sheets, vacuum our floors, and scrub our showers—but somehow, the mattress gets skipped. The truth is, learning how to clean a mattress isn’t just for spring cleaning. It’s essential for your health, your sleep, and the longevity of your investment. From late-night Netflix marathons to allergy season in Denver, your mattress sees more action than you might think.
Over time, it becomes a silent collector of dust mites, skin cells, body oils, sweat, and the occasional snack crumb. And that’s before we even talk about odor. A fresh, clean mattress supports better rest, fewer allergy flare-ups, and yes—makes your entire bedroom feel more put together. It’s not about deep cleaning for guests. It’s about doing it for you.
Why Regular Mattress Cleaning Matters
Mattresses absorb everything. Every hour of sleep, every lazy Sunday, and every morning coffee spill. Without proper care, you’re sleeping on a surface filled with invisible grime. Learning how to clean a mattress naturally and consistently isn’t just helpful—it’s necessary.
Over time, your mattress builds up more than just dust. Think bacteria, sweat stains, skin flakes, and allergens. If you've got pets or live in a dry climate like Colorado, you're also dealing with dander and dust that settles deep into the fabric. All of this affects your air quality and can mess with your sleep patterns.
Knowing how to clean mattress stains, neutralize odors, and stop bacteria from spreading is a simple way to protect your health. Clean mattresses mean fewer sniffles, fewer breakouts, and less tossing and turning at night. It’s a step people skip—but once you get into the habit, it changes everything.
What You’ll Need Before You Start
You don’t need fancy gadgets or a TikTok cleaning haul to get started. Most of the tools for learning how to clean a mattress are probably already in your house. If not, they’re easy to grab from any local store in Denver or even during your next Target run.
Before you begin, make sure you’ve got this quick checklist ready. The right supplies make the whole process faster, cleaner, and way more effective—especially if you're dealing with things like sweat stains or need to remove odor from a mattress.
- Vacuum with upholstery attachment – A regular vacuum won’t cut it. You’ll need that special tool to pull dust and dirt from seams and stitching.
- Baking soda – The MVP of odor control. It’s cheap, effective, and chemical-free, making it great if you want to clean a mattress naturally.
- Enzyme cleaner or dish soap – For spot treating anything stubborn. If you're dealing with pets or kids, this is your go-to for learning how to clean urine from a mattress.
- Cleaning cloths or sponges – Use something that won’t scratch or spread the stain. Old cotton T-shirts work in a pinch.
- White vinegar – Still trending on eco-cleaning TikTok for a reason. Perfect for tackling odor and bacteria.
- Cold water – Helps lift stains without setting them deeper into the fabric.
With these tools in hand, you’re ready to take on anything your mattress throws at you. From unexpected spills to everyday dust, this kit has you covered—no filter or cleaning hack needed.
How to Clean a Mattress Step by Step

This is your go-to guide for taking your bed from “meh” to fresh. Each step is simple but powerful—perfect for tackling deep dust, tough stains, or just giving your sleep setup a well-earned refresh. And if you’re dealing with dry air and dust in places like Denver, this routine helps even more. Ready? Here’s how to clean it right.
1. Strip the Bed and Wash the Bedding
Start with a clean slate. Remove all sheets, pillowcases, blankets, and mattress covers. Wash them in hot water to kill bacteria and eliminate allergens like dust mites. If you suffer from allergies, this step alone can make a huge difference in how you sleep. Don’t skip washing comforters and mattress protectors either—they hold just as much grime. This is the first move in learning how to clean a mattress the right way.
2. Vacuum the Mattress Thoroughly
Grab your vacuum and use the upholstery attachment. Cover every inch of the surface, the sides, and especially the seams. Dust, skin flakes, and pet hair hide there like it’s their day job. Go over the surface once vertically and once horizontally. This is a key move for anyone wondering how to vacuum a mattress effectively. It pulls out the buildup you can’t see—and that’s what messes with your air quality.
3. Spot Clean Any Stains Carefully
This is where you tackle the big stuff: sweat stains, urine stains, and even blood spots. Use an enzyme cleaner or mix white vinegar with cold water. Blot the stain—don’t rub. That just pushes it deeper. For older marks, sprinkle baking soda after applying the cleaner and let it fizz. It’s a solid trick if you're trying to figure out how to clean mattress stains without damaging the fabric. Keep it light, and don’t soak the surface. A damp mattress can grow mold fast.
4. Deodorize With Baking Soda
Sprinkle baking soda generously over the entire mattress. Use at least a full cup if you haven’t cleaned it in a while. This step is essential for anyone wondering how to remove odor from a mattress. Let it sit for several hours—overnight if you can. The longer it rests, the more moisture and smells it absorbs. Think of this like your mattress’s dry shampoo moment.
5. Optional Sunlight Exposure
If you have a sunny window—or even better, a safe outdoor space—expose your mattress to natural sunlight. UV rays help kill bacteria and break down odors. In sunny states like Colorado, this can speed up drying and freshening. It’s an underrated but effective move, especially after spot-cleaning stains or if your mattress smells musty.
6. Vacuum Again to Remove Baking Soda
Once the baking soda has done its job, vacuum it all up thoroughly. Make sure there’s no powder left behind in the seams or stitching. This is the final clean sweep before putting your bed back together. It’s simple, but it’s the difference between a half-clean and a totally refreshed surface. For those learning how to deep clean a mattress, this second vacuum is key.
7. Flip or Rotate Your Mattress
If your mattress allows it, flip or rotate it 180 degrees. This helps with even wear and extends the life of your bed. Not all mattresses can be flipped (like memory foam or hybrids), but rotating is usually safe and smart. Skipping this step can lead to dips and sagging. Regular rotation pairs well with your long-term mattress maintenance game.
8. Protect With a Mattress Protector
This is your best defense against future spills, sweat, and allergens. A good mattress protector blocks dust and moisture before it sinks in. It’s especially useful for families with kids, pets, or anyone prone to late-night snacking. You’ll thank yourself later when you’re not googling how to clean urine from a mattress again.
9. Use Fresh Fitted Sheets and Air Out the Room
Wrap up the process with a fresh, clean set of fitted sheets. Light, breathable fabrics work best. Open a window or run a fan to help any lingering moisture or smells clear out. This final step isn’t just about looks—it’s about finishing off your clean space with a healthy, fresh sleep vibe. It’s the easiest part, but it ties everything together like the last scene in a great Netflix series.
How Often Should You Clean Your Mattress?

Think of your mattress like your favorite hoodie—it feels better the more you clean it. Experts suggest doing a full clean every six months. But if you have allergies, live in a dusty area like Denver, or share your bed with pets, you might want to do it more often.
Between deep cleans, keep things fresh with monthly vacuuming. This helps remove surface debris, hair, and dust before it settles deep. Got a spill? Don’t wait. Spot cleaning stains right away makes them easier to manage and keeps your mattress in better shape long-term. These simple steps can stretch the lifespan of your bed and improve how well you sleep every night.
Tips for Specific Mattress Types
Not all mattresses are built the same, and how you clean yours depends on what it’s made of. Some materials need more care. Others dry slower or can get damaged with the wrong method. Here’s how to stay on the safe side, no matter what type you sleep on.
Cleaning a Memory Foam Mattress
Memory foam holds onto moisture like a sponge, which means less is more. If you're figuring out how to clean a memory foam mattress, avoid soaking it. Use light sprays or damp cloths—never pour liquids directly on the surface.
Focus on spot cleaning and deodorizing with baking soda. Give it extra time to dry, and speed things up with a fan or sunlight if possible. Just skip the steamers or wet vacs—they push too much moisture into the foam.
Cleaning a Pillow Top or Hybrid Mattress
Pillow tops and hybrid mattresses usually have a plush upper layer that absorbs stains quickly. If you need to know how to clean mattress stains on these types, blot the area gently and avoid scrubbing. Too much pressure can damage the fabric or push dirt deeper.
Use gentle products and let them air dry fully. These mattresses benefit from extra airflow, especially in places like Colorado where the dry climate helps things dry faster. Just make sure both layers—top and base—get attention during cleaning.
Natural and DIY Cleaning Alternatives
If you're into low-tox living or just want to skip harsh chemicals, there are plenty of ways to clean smart. Knowing how to clean a mattress naturally is a win for your sleep and your skin—especially if you’re sensitive to fragrances or allergic to synthetic cleaners.
Start with the classics. Baking soda is a natural deodorizer that pulls out moisture and neutralizes smells. Just sprinkle it generously, let it sit, and vacuum it up. Next up, white vinegar. Mix it with cold water and spray lightly to break down bacteria and surface stains. Follow that with a bit of lemon juice if you're going for that fresh, clean scent without artificial fragrances.
This kind of DIY approach is popular for a reason—it works. And for households in Denver where dry skin is common, using fewer chemicals means less irritation. These methods are cheap, effective, and a solid alternative if you want to keep your mattress fresh without loading up on store-bought sprays.
Common Mistakes to Avoid When Cleaning a Mattress
Cleaning your mattress is easy—until it isn’t. Skip these common mistakes to avoid turning a refresh into a regret.
First, using too much liquid. Whether it’s water, vinegar, or a store-bought cleaner, too much moisture leads to mold. This is especially risky if your mattress doesn’t get full airflow or if you don’t dry it properly. Second, don’t forget to let the mattress dry all the way. This sounds basic, but half-dry foam can hold bacteria longer than your last takeout container.
Next, don’t scrub stains aggressively. It can break down the fibers and actually make them worse. Blot gently and give the cleaner time to work. And finally, people always forget the edges. The seams and sides trap dust and pet dander. If you’re learning how to deep clean a mattress, give those areas just as much attention as the top surface.
Final Thoughts on Keeping Your Mattress Clean

Learning how to clean a mattress is more than just a weekend chore—it’s a way to protect your health, sleep better, and extend the life of something you use every single day. From deep mattress stain removal to natural deodorizing with baking soda and vinegar, each step adds up to a fresher, healthier place to rest. Plus, with allergy seasons hitting hard—especially in places like Denver—keeping your mattress free of dust, pet dander, and bacteria can make a noticeable difference in your day-to-day comfort.
Setting a cleaning schedule—say, every six months—can save you from bigger issues down the road. Spot clean stains early, vacuum monthly, and don’t forget the sides. And if your mattress has reached the point of no return, it might be time for an upgrade. Visit Alpine Outlets in Denver, Colorado to explore a wide range of high-quality, discount mattresses that fit your sleep style and your budget. Your best sleep starts with a clean, comfortable base—and we’re here to help you find it.